Since every patient’s situation is unique, the cost of oral appliance therapy varies, based on the type of appliance prescribed and the type of insurance you have. But, generally speaking, prescription, custom-fit mandibular advancing appliances cost roughly $2000 to $4000 including dentist fees. Your medical insurance may cover some or all of the cost of the oral appliance. Your out-of-pocket cost will depend on your insurance deductible as well. It is always a good idea to check with your insurance company first.